What We Test

Here's everything we test in your OneTwenty Membership

Up to 165 data points per year across blood, urine, and smart device metrics — organized by system, interpreted by physicians, and built into a protocol designed around you.

What Is A Biomarker? & Why Does It Matter?

Blood Data. Live Data. One Complete Picture.

Most people have no idea how their body is actually performing. Standard care measures for disease, not optimization, which means you can feel off, plateau, or age faster than you should while everything looks "normal" on paper.

OneTwenty measures differently.

We track biomarkers across the systems that drive how you feel, perform, and age: hormones, metabolism, cardiovascular health, inflammation, and nutrient status. Your full panel runs annually. Between draws, your smart metrics and prior lab results determine which targeted panels you get each quarter, so we're always testing what's most relevant to you right now.

Everything feeds into your OneTwenty Health Score, a single evolving number that combines your lab results with your wearable and lifestyle data, tracks your trajectory, and tells you what's driving the change.

Below is every biomarker we measure, organized by body system.

Most people have never had a real picture of their health. Standard checkups test a fraction of what matters, flag nothing until something is already wrong, and hand you results with no explanation and no plan. OneTwenty works differently. We test the biomarkers that actually predict how you age, how you feel, and how your body is functioning right now -- across hormones, metabolism, cardiovascular health, inflammation, organ function, and more. Then we combine those results with your smart device data, lifestyle, and goals to build a protocol that's specific to your biology.

Every category below represents a system in your body. Each one tells a different part of your story. Together, they give you something most people never get: a complete, actionable picture of what's actually going on inside.

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Chronic low-grade inflammation is one of the biggest drivers of aging and disease. These markers reveal whether your immune system is overactive, underreacting, or silently inflamed — so you can intervene before symptoms appear.

32 biomarkers available

Immune & Inflamation

Immune & Inflammation

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Your kidneys filter your blood continuously and regulate blood pressure, electrolytes, and waste removal. These markers catch early kidney dysfunction and hydration imbalances before they show up as symptoms.

15 biomarkers available

Kidney & Urinary

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Sleep, recovery, heart rate variability, activity, and other real-time data pulled from your connected devices. These metrics give us a continuous window into how your body is actually performing day-to-day — filling the gaps between lab draws with live signal.

22 biomarkers available

Smart Metric

Daily Step Count

Weekly Exercise Minutes

Continuous Glucose (CGM)

Muscle Mass

Lean Muscle Mass

Active Calories

Cardiorespiratory Fitness (VO₂ max estimate)

Active Minutes

Fat-to-Muscle Ratio (FMR)

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Hormones govern your energy, mood, metabolism, libido, sleep, and how fast you age. These markers go far beyond what your GP checks — covering testosterone, estrogen, thyroid, adrenal, and reproductive health in full.

22 biomarkers available

Hormones & Reproductive

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Most heart attacks happen in people whose standard cholesterol looked normal. These markers go deeper — assessing lipid particle size, arterial inflammation, insulin resistance, and metabolic risk years before a cardiac event.

16 biomarkers available

Cardiometabolic

Why This Metric Is Important?

Assesses your body’s fat, muscle, bone, and water composition. Helps track weight management, hydration, and metabolic health.

Your liver processes everything you eat, drink, and absorb. These markers assess detox capacity, enzyme activity, and gut-related inflammation — catching dysfunction early before it compounds into serious damage.

22 biomarkers available

Liver & Digestion

Lifelong Optimization

Join The

Closed Beta

We are currently in closed beta with limited capacity.

Open Beta · Launching June

HSA/FSA Approved

50% off for Founding Members

Hey Nick,

Your Quarterly Review

ApoB Density +12% → Elevated cardiovascular risk

Resting HR +6 bpm → Possible overtraining or stress

Sleep Time -42 min → Reduced nightly recovery

BMI Shift -1.8% → Healthy weight improvement

HRV Recovery +22ms → Stronger stress resilience

→ Suggesting root cause (AI Coming soon)

Lifelong Optimization

Join The

Closed Beta

We are currently in closed beta with limited capacity.

First Closed Beta Full
·
Accepting Reservations for Second Cohort

HSA/FSA Approved

50% off for Founding Members

Hey Nick,

Your Quarterly Review

ApoB Density +12% → Elevated cardiovascular risk

Resting HR +6 bpm → Possible overtraining or stress

Sleep Time -42 min → Reduced nightly recovery

BMI Shift -1.8% → Healthy weight improvement

HRV Recovery +22ms → Stronger stress resilience

→ Suggesting root cause (AI Coming soon)

Frequently Asked Questions

Clarity before

you commit

Answers on setup, scale, and support to remove blockers.

What’s included in the membership?

Do you accept HSA and FSA?

Do I have to take medications?

Is OneTwenty available in my state/country?

Is my health data secure? (HIPAA Standards)

Do you treat medical conditions?

Why can't I use my insurance for these labs?

Y

ur

Data

Your

D

e

ices

Your

Longevity

OneTwenty

Live guidance for sleep, hormones, and weight powered by your wearables, smart devices and blood work

Important Details:

*Up to 165 lab data points per year. Exact number varies based on your baseline results and which biomarkers your physician retests each quarter.

**Due to state-specific lab draw requirements in New York and New Jersey, testing is conducted twice per year instead of quarterly. Pricing reflects the higher cost of at-home phlebotomy in these states.


Disclaimer:

OneTwenty is a health technology company. We are not a medical provider, laboratory, or pharmacy. We provide data and tools to help you make informed decisions about your own health and better understand your biological needs.

All clinical services, including lab testing, telehealth consultations, and prescription fulfillment, are provided exclusively by independent, licensed third parties.


OneTwenty facilitates secure communication between you and these providers. OneTwenty does not prescribe medications, provide diagnoses, or offer medical treatment. While we provide personalized insights and protocols, these are not a substitute for professional medical advice.

Always consult your primary care physician before making changes to your health regimen. OneTwenty does not replace your relationship with your physician.

Y

ur

Data

Your

D

e

ices

Your

Longevity

OneTwenty

Live guidance for sleep, hormones, and weight powered by your wearables, smart devices and blood work

Important Details:

*Up to 165 lab data points per year. Exact number varies based on your baseline results and which biomarkers your physician retests each quarter.

**Due to state-specific lab draw requirements in New York and New Jersey, testing is conducted twice per year instead of quarterly. Pricing reflects the higher cost of at-home phlebotomy in these states.


Disclaimer:

OneTwenty is a health technology company. We are not a medical provider, laboratory, or pharmacy. We provide data and tools to help you make informed decisions about your own health and better understand your biological needs.

All clinical services, including lab testing, telehealth consultations, and prescription fulfillment, are provided exclusively by independent, licensed third parties.


OneTwenty facilitates secure communication between you and these providers. OneTwenty does not prescribe medications, provide diagnoses, or offer medical treatment. While we provide personalized insights and protocols, these are not a substitute for professional medical advice.

Always consult your primary care physician before making changes to your health regimen. OneTwenty does not replace your relationship with your physician.

Y

ur

Data

Your

D

e

ices

Your

Longevity

OUTLIVE.

Live guidance for sleep, hormones, and weight powered by your wearables, smart devices and blood work

Important Details:

*Up to 165 lab data points per year. Exact number varies based on your baseline results and which biomarkers your physician retests each quarter.

**Due to state-specific lab draw requirements in New York and New Jersey, testing is conducted twice per year instead of quarterly. Pricing reflects the higher cost of at-home phlebotomy in these states.


Disclaimer:

OneTwenty is a health technology company. We are not a medical provider, laboratory, or pharmacy. We provide data and tools to help you make informed decisions about your own health and better understand your biological needs.

All clinical services, including lab testing, telehealth consultations, and prescription fulfillment, are provided exclusively by independent, licensed third parties.


OneTwenty facilitates secure communication between you and these providers. OneTwenty does not prescribe medications, provide diagnoses, or offer medical treatment. While we provide personalized insights and protocols, these are not a substitute for professional medical advice.

Always consult your primary care physician before making changes to your health regimen. OneTwenty does not replace your relationship with your physician.

Stop Guessing Your Health

Live guidance for sleep, hormones, and weight powered by your wearables, devices + blood work.

Join Beta

Join Beta Waitlist

Stop Guessing Your Health

Live guidance for sleep, hormones, and weight powered by your wearables, devices + blood work.

Join Beta

Join Beta Waitlist